To assess the reliability of ICH score for predicting the mortality rate in acute intracerebral hemorrhage patients, in a rural based hospital, Jhalawar

Background: A simple clinical scale of intracerebral hemorrhage, comprising the Glasgow Coma Scale score, age, Infratentorial origin, ICH volume, and Intraventricular hemorrhage, was recently shown to predict 30-day mortality. We studied how well the original ICH Score would predict morbidity and mortality. Materials and methods: We did a retrospective study, in which records of all the patients with acute intracerebral hemorrhage were reviewed. Components of the ICH Score were recorded along with other clinical characteristics. Outcome was analyzed using modified ranking scale. Results: The mean age was 69  15 years with 45.4% males and 54.6% females. Common risk factors were smoking, diabetes mellitus and hypertension. Supratentorial lesions were 93.25% and Infratentorial lesions were 6.74 %. The overall 30 day mortality rate for ICH was 29.03%. Important predictors of mortality were, GCS score on admission (P<0.0001), hematoma volume >30ml (P <0.0001), Intraventricular extension (P <0.0001), and ICH score (P <0.0001). Conclusion: The study shows ICH score is very useful in prognostication. The overall mortality rate with ICH is similar to the previously published studies.

Retrospective study of common prevalent risk factors among female patients presented with acute coronary syndrome.

Background and Objective : Acute coronary syndrome (ACS) is characterized by classical history of ischaemic chest pain, apprehension and sweating with definite Electro-Cardio gram (ECG) evidence or cardiac marker of ischaemia. The risk factors for Coronary Artery Disease (CAD) are modifiable and non-modifiable. CAD is a major cause of disability and the leading cause of death in women. The objective of our study was to assess the impact of various risk factors in women presented with ACS. Method: A total of 100 female patients of ACS and twenty healthy females were taken as control. The mean age of women presented with ACS was 62.62 years and all have attained menopause. Result: The prevalence of major risk factors of ACS in women are hypertension (78%), stress (74%), obesity (46%), sedentary habits (38%), genetic predisposition (36%), diabetes (32%) and tobacco use (18%),higher socio-economic status (74%). Significantly (P <0.05) high levels of total cholesterol, triglycerides along with reduced High Density Lipid (HDL). Conclusion: The prevalence of C - reactive protein (CRP) Positivity (>6 mg/L) is significant in women with (92%) as compared to healthy women (20%).